Endocrine Abstracts

Introduction: Multiple endocrine neoplasia type 1 is a rare inherited tumor syndrome defined most frequently by the association of primary hyperparathyroidism, gastro-entero-pancreatic tract endocrine neoplasia and anterior pituitary gland adenoma and less commonly by neuroendocrine tumor of the adrenal cortex, thymus and bronchis. Association to non-endocrine tumors affecting the skin, glial cell, smooth muscle or breast cancer has been described. As far as we know, only one ...

Introduction: The French National Institute of Cancer (INCa) launched supported by the Ministry of Health in 2008 a program for the recognition of national networks for the management of rare cancers. Among the 23 selected networks COMETE-Cancer was recognized by INCa in 2009 for Adrenocortical carcinoma (ACC) and malignant pheochromocytoma/paraganglioma (MPP). At that time 60–120 new ACC/year and 30 new MPP/year were expected at the national level....

Background: Familial chylomicronaemia syndrome (FCS) is a rare, inherited disorder characterised by impaired clearance of triglyceride (TG)-rich lipoproteins from plasma, leading to severe hypertriglyceridaemia (HTG), which have major effects on both physical and mental health, and a markedly increased risk of acute pancreatitis. A large overlap in the phenotype between FCS and multifactorial chylomicronaemia syndrome (MCS) contributes to the inconsistency in how patients are ...

Non-alcoholic fatty liver disease (NAFLD) is commonly associated with obesity, metabolic syndrome and type 2 diabetes. NAFLD is also seen in patients with endocrinopathies. However, the relationship between endocrinopathies and the development of NAFLD is not well known. Both GH and IGF1 are believed to be involved in the regulation of hepatic lipid metabolism.Objective: In this study, we set out to determine whether liver fat content (LFC) was associate...